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SOX8 Antibody - C-terminal region: FITC (P100732_P050-FITC)

Product Specifications

Gene Name

SRY (sex determining region Y) -box 8

Gene Aliases

MGC24837

Gene ID

30812

Swiss Prot

P57073

Accession Number

NP_055402

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human SOX8

Target

SOX8 is a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. It may act as a transcriptional activator after forming a protein complex with other proteins. This protein may be involved in brain development and function. Haploinsufficiency for this protein may contribute to the mental retardation found in haemoglobin H-related mental retardation (ART-16 syndrome) .This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional activator after forming a protein complex with other proteins. This protein may be involved in brain development and function. Haploinsufficiency for this protein may contribute to the mental retardation found in haemoglobin H-related mental retardation (ART-16 syndrome) .

Partner Proteins

JAM2; PIDD1; NOD1; UBC; MMP1; SOX2; HOXC11; UTF1; PAX3; OLIG2; HHEX; POU3F3; TCF12; DLX5; SP1; NR5A1; JUN; POU5F1; EGR2; CEBPA

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

WB

Concentration

0.5 mg/mL

Homology

Cow: 92%; Dog: 92%; Guinea Pig: 85%; Horse: 92%; Human: 100%; Mouse: 78%; Rat: 85%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

47kDa

Shipping Conditions

Wet Ice

Protein Length

446

NCBI Gene Symbol

SOX8

Protein Name

Transcription factor SOX-8

Nucleotide Accession Number

NM_014587

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