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SOX8 Antibody - C-terminal region : FITC (P100732_P050-FITC)

Selected Variant

P100732_P050-FITC

Size: 100 µL

Product Specifications

Gene Name

SRY (sex determining region Y) -box 8

Gene Aliases

MGC24837

Gene ID

30812

Swiss Prot

P57073

Accession Number

NP_055402

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human SOX8

Target

SOX8 is a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. It may act as a transcriptional activator after forming a protein complex with other proteins. This protein may be involved in brain development and function. Haploinsufficiency for this protein may contribute to the mental retardation found in haemoglobin H-related mental retardation (ART-16 syndrome) .This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional activator after forming a protein complex with other proteins. This protein may be involved in brain development and function. Haploinsufficiency for this protein may contribute to the mental retardation found in haemoglobin H-related mental retardation (ART-16 syndrome) .

Partner Proteins

JAM2; PIDD1; NOD1; UBC; MMP1; SOX2; HOXC11; UTF1; PAX3; OLIG2; HHEX; POU3F3; TCF12; DLX5; SP1; NR5A1; JUN; POU5F1; EGR2; CEBPA

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

WB

Concentration

0.5 mg/ml

Homology

Cow: 92%; Dog: 92%; Guinea Pig: 85%; Horse: 92%; Human: 100%; Mouse: 78%; Rat: 85%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

47kDa

References & Citations

Wissmuller, S., (2006) (er) Nucleic Acids Res. 34 (6), 1735-1744

Shipping Conditions

Wet Ice

Protein Length

446

NCBI Gene Symbol

SOX8

NCBI GB Accession Number

SOX8

Host or Source

Rabbit

Protein Name

Transcription factor SOX-8

Nucleotide Accession Number

NM_014587

Peptide Sequence

ASPTETGPPRPHIKTEQPSPGHYGDQPRGSPDYGSCSGQSSATPAAPAGP

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