SOX8 Antibody - C-terminal region: FITC (P100732_P050-FITC)
Product Specifications
Gene Name
SRY (sex determining region Y) -box 8
Gene Aliases
MGC24837
Gene ID
30812
Swiss Prot
P57073
Accession Number
NP_055402
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse
Immunogen
The immunogen is a synthetic peptide directed towards the C terminal region of human SOX8
Target
SOX8 is a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. It may act as a transcriptional activator after forming a protein complex with other proteins. This protein may be involved in brain development and function. Haploinsufficiency for this protein may contribute to the mental retardation found in haemoglobin H-related mental retardation (ART-16 syndrome) .This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional activator after forming a protein complex with other proteins. This protein may be involved in brain development and function. Haploinsufficiency for this protein may contribute to the mental retardation found in haemoglobin H-related mental retardation (ART-16 syndrome) .
Partner Proteins
JAM2; PIDD1; NOD1; UBC; MMP1; SOX2; HOXC11; UTF1; PAX3; OLIG2; HHEX; POU3F3; TCF12; DLX5; SP1; NR5A1; JUN; POU5F1; EGR2; CEBPA
Clonality
Polyclonal
Conjugation
FITC: Fluorescein Isothiocyanate
Type
Polyclonal Antibody
Applications
WB
Concentration
0.5 mg/mL
Homology
Cow: 92%; Dog: 92%; Guinea Pig: 85%; Horse: 92%; Human: 100%; Mouse: 78%; Rat: 85%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
47kDa
Shipping Conditions
Wet Ice
Protein Length
446
NCBI Gene Symbol
SOX8
Protein Name
Transcription factor SOX-8
Nucleotide Accession Number
NM_014587
Curated Selection
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