NR3C2 Antibody - C-terminal region : FITC (P100726_P050-FITC)
Selected Variant
P100726_P050-FITC
Size: 100 µL
Product Specifications
Gene Name
Nuclear receptor subfamily 3, group C, member 2
Gene Aliases
MR, MCR, MLR, NR3C2VIT
Gene ID
4306
Swiss Prot
B0ZBF5
Accession Number
NP_001159576
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Horse
Immunogen
The immunogen is a synthetic peptide directed towards the C terminal region of human NR3C2
Target
NR3C2 is a receptor for both mineralocorticoids (MC) such as aldosterone and glucocorticoids (GC) such as corticosterone or cortisol. It binds to mineralocorticoid response elements (MRE) and transactivates target genes. The effect of MC is to increase ion and water transport and thus raise extracellular fluid volume and blood pressure and lower potassium levels.
Partner Proteins
RABAC1; RXRA; HSP90AA1; ACSL1; UBC; SRC; PPP5C; PPID; FKBP5; FKBP4; STUB1; AIP; TRIM24; NRIP1; DNAJC7; CAND1; SUMO1; UBE2I; EIF3I; PROX1; PIAS1; PIAS3; HSPA4; PTGES3; AR; NR3C1; ACTA1; ACTG1
Clonality
Polyclonal
Conjugation
FITC: Fluorescein Isothiocyanate
Type
Polyclonal Antibody
Applications
WB
Concentration
0.5 mg/ml
Homology
Cow: 92%; Horse: 100%; Human: 100%; Mouse: 100%; Rat: 100%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
94kDa
Shipping Conditions
Wet Ice
Protein Length
867
NCBI Gene Symbol
NR3C2
NCBI GB Accession Number
NR3C2
Host or Source
Rabbit
Protein Name
Mineralocorticoid receptor Ensembl ENSP00000423510
Nucleotide Accession Number
NM_001166104
Peptide Sequence
VSDLLEFCFYTFRESHALKVEFPAMLVEIISDQLPKVESGNAKPLYFHRK
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