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IRF2 Antibody - N-terminal region : FITC (P100613_P050-FITC)

Selected Variant

P100613_P050-FITC

Size: 100 µL

Product Specifications

Gene Name

Interferon regulatory factor 2

Gene Aliases

IRF-2

Gene ID

3660

Swiss Prot

P14316

Accession Number

NP_002190

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Sheep, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human IRF2

Target

IRF2 encodes interferon regulatory factor 2, a member of the interferon regulatory transcription factor (IRF) family. IRF2 competitively inhibits the IRF1-mediated transcriptional activation of interferons alpha and beta, and presumably other genes that employ IRF1 for transcription activation. However, IRF2 also functions as a transcriptional activator of histone H4.

Partner Proteins

IRF1; SUMO2; SUMO3; PRDM1; MDM2; FKBP7; HSP90AA1; APP; IRF2BP2; IRF2BP1; UBC; FOXK1; IRF2BPL; HCFC2; ATG7; AP5Z1; PPP3CB; PPP3CA; FOXK2; HCFC1; KAT2B; EP300; IRF8; STAT1; RELA; NFKB1; HMGN1; HMGB1; CSNK2A1; BRD7; PRKACA; KAT2A

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

WB, IHC

Concentration

0.5 mg/ml

Homology

Cow: 92%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 92%; Rat: 100%; Sheep: 92%; Zebrafish: 90%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

39kDa

References & Citations

Oshima, S., et al., (2004) Mol. Cell. Biol. 24 (14), 6298-6310

Shipping Conditions

Wet Ice

Protein Length

349

NCBI Gene Symbol

IRF2

NCBI GB Accession Number

IRF2

Host or Source

Rabbit

Protein Name

Interferon regulatory factor 2

Nucleotide Accession Number

NM_002199

Peptide Sequence

APLFRNRAIHTGKHQPGVDKPDPKTWKANFRCAMNSLPDIEEVKDKSIKK

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