PION Antibody : Biotin (OAPB01240-Biotin)
Product Specifications
Gene Aliases
PION
Gene ID
54103
Swiss Prot
A4D1B5
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
The immunogen for anti-PION antibody: antibody was raised against a 19 amino acid peptide near the carboxy terminus of human PION.
Target
Gamma-secretase activating protein
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
IHC, ELISA, WB
Purification
Affinity chromatography purified via peptide column
Concentration
1 mg/ml
Homology
Human; Mouse; Rat
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
References & Citations
Ponte P, Gonzalez-DeWhitt P, Schilling J, et al. A new A4 amyloid mRNA contains a domain homologous to serine proteinase inhibitors. Nature1988; 331:525-77.; Selkoe DJ. Cell biology of the amyloid beta-protein precursor and the mechanism of Alzheimer's disease. Annu. Rev. Cell Biol.1994; 10:373-403.; He G, Luo W, Li P, et al. Gamma-secretase activating protein is a therapeutic target for Alzheimer's diease. Nature2010; 467:95-9.
Shipping Conditions
Wet Ice
Specificity
Multiple isoforms of PION are known to exist. PION antibody is predicted to not cross-react with other F-box protein family members.
NCBI Gene Symbol
PION
NCBI GB Accession Number
PION
Host or Source
Rabbit
Protein Name
Gamma-secretase-activating protein
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNC880460-100 1x 100 µL
CD44 Standard (156-3C11), CF488A conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC680266-100 1x 100 µL
Human IgG Immunoglobulin (IG266), CF568 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
