KLOTHO Antibody : FITC (OAPB01225-FITC)
Product Specifications
Gene Aliases
Alp, alpha-kl
Gene ID
16591
Swiss Prot
O35082
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
The immunogen for anti-KLOTHO antibody: antibody was raised against a 16 amino acid peptide near the center of human KLOTHO.
Target
Anti-agining hormone in glycosidase1 superfamily
Clonality
Polyclonal
Conjugation
FITC: Fluorescein Isothiocyanate
Type
Polyclonal Antibody
Applications
IHC, WB
Purification
Affinity chromatography purified via peptide column
Concentration
1 mg/ml
Homology
Human; Mouse; Rat
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
References & Citations
Kuro-o M, Matsumura Y, and Aizawa H. Mutation of the mouse klotho gene leads to a syndrome resembling ageing. Nature1997; 390:45-51.; Kurosu H, Yamamoto M, Clark JD, et al. Suppression of aging in mice by the hormone Klotho. Science2005; 309:1829–33. ; Liu H, Fergusson MM, Castilho RM, et al. Augmented Wnt signaling in a mammalian model of accelerated aging. Science 2007; 317:803–6. ; Wolf I, Levanon-Cohen S, Bose S, et al. Klotho: a tumor suppressor and a modulator of the IGF-1 and FGF pathways in human breast cancer. Oncogene2008; 27:7094–105.
Shipping Conditions
Wet Ice
Specificity
Two isoforms of KLOTHO are known to exist.
Applications Notes
KLOTHO antibody can be used for detection of KLOTHO by Western blot at 1 - 2 ug/ml. (Optimal dilution should be determined by user)
NCBI Gene Symbol
KL
NCBI GB Accession Number
Kl
Host or Source
Rabbit
Protein Name
Klotho
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