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LXR-A Antibody : HRP (OAPB01031-HRP)

Selected Variant

OAPB01031-100UG-HRP

Size: 0.1 mg

Product Specifications

Gene Aliases

LXRA, LXR-a, RLD-1

Gene ID

10062

Swiss Prot

Q13133

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

The immunogen for anti-LXR-A antibody: antibody was raised against a 15 amino acid peptide from near the amino terminus human LXR-A.

Target

Liver X receptor A

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

ELISA, WB, IHC

Purification

Affinity chromatography purified via peptide column

Concentration

0.6-0.7 mg/ml

Homology

Human; Mouse; Rat

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

References & Citations

Willy PJ, Umesono K, Ong ES, et al. LXR, a nuclear receptor that defines a distinct retinoid response pathway. Genes Dev.1995; 9:1033-45.; Edwards PA, Kennedy MA, and Mak PA. LXRs; Oxysterol-activated nuclear receptors that regulate genes controlling lipid homeostasis. Vasc. Pharmacol.2002; 38:249-56.; Bensinger SJ and Tontonoz P. Integration of metabolism and inflammation by lipid-activated nuclear receptors. Nature2008; 454:470-7.; Villablanca EJ, Raccosta L, Zhou D, et al. Tumor-mediated liver X receptor-a activation inhibits CC chemokine reeptor-7 expression on dendritic cells and dampens antitumor responses. Nature Med.2010; 16:98-106.

Shipping Conditions

Wet Ice

Applications Notes

LXR-A antibody can be used for detection of LXR-A by Western blot at 1 - 2 ug/ml. (Optimal dilution should be determined by user)

NCBI Gene Symbol

NR1H3

NCBI GB Accession Number

NR1H3

Host or Source

Rabbit

Protein Name

Oxysterols receptor LXR-alpha

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