PICALM Antibody : HRP (OAPB01019-HRP)
Product Specifications
Gene Aliases
LAP, CALM, CLTH
Gene ID
8301
Swiss Prot
E9PN05
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
The immunogen for anti-PICALM antibody: antibody was raised against a 15 amino acid peptide from near the amino terminus of human PICALM.
Target
Phosphatidylinositol-binding clathrin assembly protein
Clonality
Polyclonal
Conjugation
HRP: Horseradish Peroxidase
Type
Polyclonal Antibody
Applications
ELISA, WB
Purification
Affinity chromatography purified via peptide column
Concentration
0.6-0.7 mg/ml
Homology
Human; Mouse; Rat
Format
Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
References & Citations
Tebar F, Bohlander SK, and Sorkin A. Clathrin assembly lymphoid myeloid leukemia (CALM) protein: localization in endocytic-coated pits, interactions with clathrin, and the impact of overexpression on clathrin mediated traffic. Mol. Biol. Cell1999; 10:2687-702.; Caudell D and Aplan PD. The role of CALM-AF10 gene fusion in acute leukemia. Leukemia2008; 22:678-85.; Harel A, Wu F, Mattson MP, et al. Evidence for CALM in directing VAMP2 trafficking. Traffic2008; 9:417-29.; Harold D, Abraham R, Hollingworth P, et al. Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer’s disease. Nat. Genet.2009; 41:1088-93.
Shipping Conditions
Wet Ice
Applications Notes
PICALM antibody can be used for detection of PICALM by Western blot at 1 - 2 ug/ml. (Optimal dilution should be determined by user)
NCBI Gene Symbol
PICALM
NCBI GB Accession Number
PICALM
Host or Source
Rabbit
Protein Name
Phosphatidylinositol-binding clathrin assembly protein
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