RIPK1 Antibody : HRP (OAPB00958-HRP)
Product Specifications
Gene Aliases
RIP, RIP1, AIEFL, IMD57, RIP-1
Gene ID
8737
Swiss Prot
Q13546
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
The immunogen for anti-RIPK1 antibody: antibody was raised against a 15 amino acid peptide from near the amino terminus of human RIPK1.
Target
Receptor-interacting kinase 1
Clonality
Polyclonal
Conjugation
HRP: Horseradish Peroxidase
Type
Polyclonal Antibody
Applications
ELISA, WB, IHC
Purification
Affinity chromatography purified via peptide column
Concentration
0.6-0.7 mg/ml
Homology
Human; Mouse; Rat
Format
Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
References & Citations
Stanger BZ, Leder P, Lee TH, et al. RIP: a novel protein containing a death domain that interacts with Fas/APO-1 (CD95) in yeast and causes cell death. Cell1995; 81:513-23.; Hsu H, Huang J, Shu HB, et al. TNF-dependent recruitment of the protein kinase RIP to the TNF receptor-1 signaling complex. Immunity1996; 4:387-96.; Meylan E, Burns K, Hofmann K, et al. RIP1 is an essential mediator of Toll-like receptor 3-induced NF-kappa B activation. Nat. Immunol.2004; 5:503-7.; Festjens N, Vanden Bergh T, Cornelis S, et al. RIP1, a kinase on the crossroads of a cell's decision to live or die. Cell Death Differ.2007;14:400-10.
Shipping Conditions
Wet Ice
Applications Notes
RIPK1 antibody can be used for detection of RIPK1 by Western blot at 1 - 2 ug/ml. (Optimal dilution should be determined by user)
NCBI Gene Symbol
RIPK1
NCBI GB Accession Number
RIPK1
Host or Source
Rabbit
Protein Name
Receptor-interacting serine/threonine-protein kinase 1
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