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IRGC Antibody : FITC (OAPB00938-FITC)

Product Specifications

Gene Aliases

IRGC (CT), Immunity-related GTPase cinema 1, Interferon-inducible GTPase 5, Iigp5, CINEMA

Swiss Prot

Q8C262

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

The immunogen for anti-IRGC antibody: antibody was raised against a 12 amino acid peptide near the carboxy terminus of human IRGC.

Target

(CT) Immunity-related GTPase cinema 1

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

ELISA, WB, ICC

Purification

Affinity chromatography purified via peptide column

Concentration

1 mg/ml

Homology

Human; Mouse; Rat

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

References & Citations

Taylor GA. IRG proteins: key mediators of interferon-regulated host resistance to intracellular pathogens. Cell Microbiol.2007; 9:1099-107.; Yamada K, Akimoto H, Ogawa Y, et al. Upregulation of immunity-related GTPase (IRG) proteins by TNF-alpha in murine astrocytes. Biochem. Biophys. Res. Commun.2009; 382:434-9.; Singh SB, et al. Human IRGM induces autophagy to eliminate intracellular mycobacteria. Science2006; 313:1438–41. ; Bekpen C, Hunn JP, Rohde C, et al. The interferon-inducible p47 (IRG) GTPases in vertebrates: loss of the cell autonomous resistance mechanism in the human lineage. Genome Biol.2005; 6:R92.

Shipping Conditions

Wet Ice

Applications Notes

IRGC antibody can be used for detection of IRGC by Western blot at 1 - 2 ug/ml. (Optimal dilution should be determined by user)

NCBI Gene Symbol

IRGC

NCBI GB Accession Number

Irgc

Host or Source

Rabbit

Protein Name

Interferon-inducible GTPase 5

Frequently Asked Questions

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