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ERBB2 Antibody : HRP (OAPB00881-HRP)

Product Specifications

Gene Name

Receptor tyrosine-protein kinase erbB-2

Gene Aliases

NEU, NGL, HER2, TKR1, CD340, HER-2, MLN 19, HER-2/neu

Gene ID

2064

Swiss Prot

P04626

Accession Number

NP_001005862.1NP_001276865.1NP_001276867.1NP_004439.2

Host

Chicken

Reactivity

Human, Mouse, Rat

Immunogen

The immunogen for anti-erbB-2 antibody: antibody was raised against a 19 amino acid peptide near the carboxy terminus of human erbB-2.

Target

V-erb-b2 erythroblastic leukemia viral oncogene homolog 2

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

ELISA, WB, IHC-P, IF, IP

Purification

Affinity chromatography purified via peptide column

Concentration

0.6-0.7 mg/ml

Homology

Human; Mouse; Rat

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

References & Citations

Baselga J and Swain SM. Novel anticancer targets: revisiting ERBB2 and discovering ERBB3. Nature Rev.2009; 9:463-475.; Slamon DJ, Clark GM, Wong SG, et al. Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu oncogene. Science1987; 235:177-82.; Vermeij J, Teugels E, Bourgain C, et al. Genomic activation of the EGFR and HER2-neu genes in a significant proportion of invasive epithelial ovarian cancers. BMC Cancer2008; 8:3.; Marmor MD, Skaria KB, and Yarden Y. Signal transduction and oncogenesis by ErbB/HER receptors. Int. J. Rad. Oncol. Biol. Phys.2004; 58:903-13.

Shipping Conditions

Wet Ice

Applications Notes

ErbB-2 antibody can be used for detection of erbB-2 by Western blot at 1 - 2 ug/ml. (Optimal dilution should be determined by user)

NCBI Gene Symbol

ERBB2

NCBI GB Accession Number

ERBB2

Host or Source

Chicken

Protein Name

Receptor tyrosine-protein kinase erbB-2

Nucleotide Accession Number

NM_001005862.2NM_001289936.1NM_001289938.1NM_004448.3

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