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EBI3 Antibody : Biotin (OAPB00812-Biotin)

Product Specifications

Gene Aliases

IL27B, IL35B, IL-27B

Gene ID

10148

Swiss Prot

Q14213

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

The immunogen for anti-EBI3 antibody: antibody was raised against a 16 amino acid peptide from near the center of human EBI3.

Target

(IN) Epstein-Barr virus induced 3 precursor

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

ELISA, WB, IHC

Purification

Affinity chromatography purified via peptide column

Concentration

1 mg/ml

Homology

Human; Mouse; Rat

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

References & Citations

Pfanz S, Timans JC, Cheung J et al. IL-27, a heterodimeric cytokine composed of EBI3 and p28 protein, induces proliferation of naïve CD4 (+) T cells. Immunity2002; 16:779-90.; Devergne O, Birkenbach M, and Kieff E. Epstein-Barr virus-induced gene 3 and the p35 subunit of interleukin form a novel heterodimeric hematopoietin. Proc. Natl. Acad. Sci. USA1997; 94:12041-6.; Niedbala W, Wei X, Cai B, et al. IL-35 is a novel cytokine with therapeutic effects against collagen-induced arthritis through the expression of regulatory T cells and suppression of Th17 cells. Eur. J. Immunol.2007; 3021-29.; Pfanz S, Hibbert L, Mattson J, et al. WSX-1 and glycoprotein 130 constitute a signal-transducing receptor for IL-27. J. Immunol.2004; 172:2225-31.

Shipping Conditions

Wet Ice

Applications Notes

EBI3 antibody can be used for the detection of EBI3 by Western blot at 2 - 4 ug/ml. (Optimal dilution should be determined by user)

NCBI Gene Symbol

EBI3

NCBI GB Accession Number

EBI3

Host or Source

Rabbit

Protein Name

Interleukin-27 subunit beta

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