EBI3 Antibody : Biotin (OAPB00812-Biotin)
Product Specifications
Gene Aliases
IL27B, IL35B, IL-27B
Gene ID
10148
Swiss Prot
Q14213
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
The immunogen for anti-EBI3 antibody: antibody was raised against a 16 amino acid peptide from near the center of human EBI3.
Target
(IN) Epstein-Barr virus induced 3 precursor
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
ELISA, WB, IHC
Purification
Affinity chromatography purified via peptide column
Concentration
1 mg/ml
Homology
Human; Mouse; Rat
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
References & Citations
Pfanz S, Timans JC, Cheung J et al. IL-27, a heterodimeric cytokine composed of EBI3 and p28 protein, induces proliferation of naïve CD4 (+) T cells. Immunity2002; 16:779-90.; Devergne O, Birkenbach M, and Kieff E. Epstein-Barr virus-induced gene 3 and the p35 subunit of interleukin form a novel heterodimeric hematopoietin. Proc. Natl. Acad. Sci. USA1997; 94:12041-6.; Niedbala W, Wei X, Cai B, et al. IL-35 is a novel cytokine with therapeutic effects against collagen-induced arthritis through the expression of regulatory T cells and suppression of Th17 cells. Eur. J. Immunol.2007; 3021-29.; Pfanz S, Hibbert L, Mattson J, et al. WSX-1 and glycoprotein 130 constitute a signal-transducing receptor for IL-27. J. Immunol.2004; 172:2225-31.
Shipping Conditions
Wet Ice
Applications Notes
EBI3 antibody can be used for the detection of EBI3 by Western blot at 2 - 4 ug/ml. (Optimal dilution should be determined by user)
NCBI Gene Symbol
EBI3
NCBI GB Accession Number
EBI3
Host or Source
Rabbit
Protein Name
Interleukin-27 subunit beta
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