TREX2 Antibody : HRP (OAPB00810-HRP)
Product Specifications
Gene Aliases
TREX2, Three prime repair exonuclease 2
Gene ID
11219
Swiss Prot
Q9BQ50
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
The immunogen for anti-TREX2 antibody: antibody was raised against a 15 amino acid peptide near the carboxy terminus of human TREX2.
Target
Three prime repair exonuclease 2
Clonality
Polyclonal
Conjugation
HRP: Horseradish Peroxidase
Type
Polyclonal Antibody
Applications
ELISA, WB, IHC
Purification
Affinity chromatography purified via peptide column
Concentration
0.6-0.7 mg/ml
Homology
Human; Mouse; Rat
Format
Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
References & Citations
Mazur DJ and Perrino FW. Identification and expression of the TREX1 and TREX2 cDNA sequences encoding mammalian 3′→5′ exonucleases. J. Biol. Chem.1999; 274:19655–60. ; Cortez D, Guntuku S, Qin J, et. al. ATR and ATRIP: partners in checkpoint signaling. Science2001; 294:1713-6; Crow YJ, Hayward BE, Parmar R, et al. Mutations in the gene encoding the 3′-5′ DNA exonuclease TREX1 cause Aicardi-Goutieres syndrome at the AGS1 locus. Nat. Genet. 2006; 38:917–20; Mazur DJ and Perrino FW. Structure and expression of the TREX1 and TREX2 3'→5' exonuclease genes. J. Biol. Chem.2001; 276:14718-27.
Shipping Conditions
Wet Ice
Applications Notes
TREX2 antibody can be used for detection of TREX2 by Western blot at 2 - 4 ug/ml. (Optimal dilution should be determined by user)
NCBI Gene Symbol
TREX2
NCBI GB Accession Number
TREX2
Host or Source
Rabbit
Protein Name
Three prime repair exonuclease 2
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