Gle1 Antibody : FITC (OAPB00807-FITC)
Product Specifications
Gene Aliases
LCCS, CAAHC, CAAHD, GLE1L, LCCS1, hGLE1
Gene ID
2733
Swiss Prot
Q53GS7
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
The immunogen for anti-Gle1 antibody: antibody was raised against a 15 amino acid peptide near the carboxy terminus of human Gle1.
Target
(CT) RNA export mediator
Clonality
Polyclonal
Conjugation
FITC: Fluorescein Isothiocyanate
Type
Polyclonal Antibody
Applications
ELISA, WB, IHC
Purification
Affinity chromatography purified via peptide column
Concentration
1 mg/ml
Homology
Human; Mouse; Rat
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
References & Citations
Murphy R and Wente SR. An RNA-export mediator with an essential nuclear export signal. Nature1996; 383:357-60.; Watkins JL, Murphy R, Emtage JL, et al. The human homologue of Saccharomyces cerevisiae Gle1p is required for poly (A) + RNA export. Proc. Natl. Acad. Sci. USA1998; 95:6779-84.; Kendirgi F, Rexer DJ, Alcazar-Roman AR, et al. Interaction between the shuttling mRNA export factor Gle1 and the nucleoporin hCG1: A conserved mechanism in the export of Hsp70 mRNA. Mol. Biol. Cell2005; 16:4304-15.; Rayala HJ, Kendirgi F, Barry DM, et al. The mRNA export factor human Gle1 interacts with the nuclear pore complex protein Nup155. Mol. Cell. Proteomics2004; 3:145-55.
Shipping Conditions
Wet Ice
Applications Notes
Gle1 antibody can be used for detection of Gle1 by Western blot at 1 - 2 ug/ml. (Optimal dilution should be determined by user)
NCBI Gene Symbol
GLE1
NCBI GB Accession Number
GLE1
Host or Source
Rabbit
Protein Name
Nucleoporin GLE1
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