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Gle1 Antibody : Biotin (OAPB00807-Biotin)

Product Specifications

Gene Aliases

LCCS, CAAHC, CAAHD, GLE1L, LCCS1, hGLE1

Gene ID

2733

Swiss Prot

Q53GS7

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

The immunogen for anti-Gle1 antibody: antibody was raised against a 15 amino acid peptide near the carboxy terminus of human Gle1.

Target

(CT) RNA export mediator

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

ELISA, WB, IHC

Purification

Affinity chromatography purified via peptide column

Concentration

1 mg/ml

Homology

Human; Mouse; Rat

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

References & Citations

Murphy R and Wente SR. An RNA-export mediator with an essential nuclear export signal. Nature1996; 383:357-60.; Watkins JL, Murphy R, Emtage JL, et al. The human homologue of Saccharomyces cerevisiae Gle1p is required for poly (A) + RNA export. Proc. Natl. Acad. Sci. USA1998; 95:6779-84.; Kendirgi F, Rexer DJ, Alcazar-Roman AR, et al. Interaction between the shuttling mRNA export factor Gle1 and the nucleoporin hCG1: A conserved mechanism in the export of Hsp70 mRNA. Mol. Biol. Cell2005; 16:4304-15.; Rayala HJ, Kendirgi F, Barry DM, et al. The mRNA export factor human Gle1 interacts with the nuclear pore complex protein Nup155. Mol. Cell. Proteomics2004; 3:145-55.

Shipping Conditions

Wet Ice

Applications Notes

Gle1 antibody can be used for detection of Gle1 by Western blot at 1 - 2 ug/ml. (Optimal dilution should be determined by user)

NCBI Gene Symbol

GLE1

NCBI GB Accession Number

GLE1

Host or Source

Rabbit

Protein Name

Nucleoporin GLE1

Frequently Asked Questions

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