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JPH1 Antibody : Biotin (OAPB00788-Biotin)

Product Specifications

Gene Aliases

JP1, JP-1, CMT2K

Gene ID

56704

Swiss Prot

Q9HDC5

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

The immunogen for anti-JPH1 antibody: antibody was raised against a 15 amino acid peptide near the carboxy terminus of human JPH1.

Target

T tubule, SR membrane, sarcoplasmic reticulum

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

ELISA, WB, IHC

Purification

Affinity chromatography purified via peptide column

Concentration

1 mg/ml

Homology

Human; Mouse; Rat

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

References & Citations

Takeshima H, Komazaki S, Nishi M, et al. Junctophilins: a novel family of junctional membrane complex proteins. Mol. Cell.2000; 6:11-22.; Kakizawa S, Kishimoto Y, Hashimoto K, et al. Junctophilin-mediated channel crosstalk essential for cerebellar synaptic plasticity. EMBO J.2007; 26:1924-33.; Nishi M, Sakagami H, Komazaki S, et al. Coexpression of junctophilin type 3 and type 4 in brain. Brain Res. Mol. Brain Res.2003; 118:102-10.; Phimister AJ, Lango J, Lee EH, et al. Conformation-dependent stability of Junctophilin 1 (JP1) and Ryanodine Receptor type 1 (RyR1) channel complex is mediated by their hyper-reactive thiols. J. Biol. Chem.2007; 282:8867-77.

Shipping Conditions

Wet Ice

Applications Notes

JPH1 antibody can be used for detection of JPH1 by Western blot at 1 - 2 ug/ml. (Optimal dilution should be determined by user)

NCBI Gene Symbol

JPH1

NCBI GB Accession Number

JPH1

Host or Source

Rabbit

Protein Name

Junctophilin-1

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