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MARCH8 Antibody : FITC (OAPB00784-FITC)

Product Specifications

Gene Aliases

MIR, CMIR, c-MIR, MARCH8, RNF178, MARCH-VIII

Gene ID

220972

Swiss Prot

Q5T0T0

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

The immunogen for anti-MARCH8 antibody: antibody was raised against a 17 amino acid peptide from near the carboxy terminus of human MARCH8.

Target

Cellular modulator of immune recognition

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

ELISA, WB, ICC

Purification

Affinity chromatography purified via peptide column

Concentration

1 mg/ml

Homology

Human; Mouse; Rat

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

References & Citations

Coscoy L, Sanchez DJ, and Ganem D. A novel class of herpesvirus-encoded membrane-bound E3 ubiquitin ligases regulates endocytosis of proteins involved in immune recognition. J. Cell Biol. 2001; 155:126573.; Goto E, Ishido S, Sato Y, et al. c-MIR, a human E3 ubiquitin ligase, is a functional homolog of herpesvirus proteins MIR1 and MIR2 and has similar activity. J. Biol. Chem.2003; 278:14657-68. ; Ohmura-Hoshino M, Goto E, Matsuki Y, et al. A novel family of membrane-bound E3 ubiquitin ligases. J. Biochem.2006; 140:147-54.; Bartee E, Mansouri M, Hovey Nerenberg BT, et al. Downregulation of major histocompatibility complex class I by human ubiquitin ligases related to viral immune evasion proteins. J. Virol.2004; 78:1109-20.

Shipping Conditions

Wet Ice

Applications Notes

MARCH8 antibody can be used for detection of MARCH8 by Western blot at 0.5 - 1 ug/ml. (Optimal dilution should be determined by user)

NCBI Gene Symbol

44993

NCBI GB Accession Number

44993

Host or Source

Rabbit

Protein Name

E3 ubiquitin-protein ligase MARCH8

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