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MARCH8 Antibody : Biotin (OAPB00784-Biotin)

Product Specifications

Gene Aliases

MIR, CMIR, c-MIR, MARCH8, RNF178, MARCH-VIII

Gene ID

220972

Swiss Prot

Q5T0T0

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

The immunogen for anti-MARCH8 antibody: antibody was raised against a 17 amino acid peptide from near the carboxy terminus of human MARCH8.

Target

Cellular modulator of immune recognition

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

ELISA, WB, ICC

Purification

Affinity chromatography purified via peptide column

Concentration

1 mg/ml

Homology

Human; Mouse; Rat

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

References & Citations

Coscoy L, Sanchez DJ, and Ganem D. A novel class of herpesvirus-encoded membrane-bound E3 ubiquitin ligases regulates endocytosis of proteins involved in immune recognition. J. Cell Biol. 2001; 155:126573.; Goto E, Ishido S, Sato Y, et al. c-MIR, a human E3 ubiquitin ligase, is a functional homolog of herpesvirus proteins MIR1 and MIR2 and has similar activity. J. Biol. Chem.2003; 278:14657-68. ; Ohmura-Hoshino M, Goto E, Matsuki Y, et al. A novel family of membrane-bound E3 ubiquitin ligases. J. Biochem.2006; 140:147-54.; Bartee E, Mansouri M, Hovey Nerenberg BT, et al. Downregulation of major histocompatibility complex class I by human ubiquitin ligases related to viral immune evasion proteins. J. Virol.2004; 78:1109-20.

Shipping Conditions

Wet Ice

Applications Notes

MARCH8 antibody can be used for detection of MARCH8 by Western blot at 0.5 - 1 ug/ml. (Optimal dilution should be determined by user)

NCBI Gene Symbol

44993

NCBI GB Accession Number

44993

Host or Source

Rabbit

Protein Name

E3 ubiquitin-protein ligase MARCH8

Frequently Asked Questions

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