MARCH8 Antibody : Biotin (OAPB00784-Biotin)
Product Specifications
Gene Aliases
MIR, CMIR, c-MIR, MARCH8, RNF178, MARCH-VIII
Gene ID
220972
Swiss Prot
Q5T0T0
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
The immunogen for anti-MARCH8 antibody: antibody was raised against a 17 amino acid peptide from near the carboxy terminus of human MARCH8.
Target
Cellular modulator of immune recognition
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
ELISA, WB, ICC
Purification
Affinity chromatography purified via peptide column
Concentration
1 mg/ml
Homology
Human; Mouse; Rat
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
References & Citations
Coscoy L, Sanchez DJ, and Ganem D. A novel class of herpesvirus-encoded membrane-bound E3 ubiquitin ligases regulates endocytosis of proteins involved in immune recognition. J. Cell Biol. 2001; 155:126573.; Goto E, Ishido S, Sato Y, et al. c-MIR, a human E3 ubiquitin ligase, is a functional homolog of herpesvirus proteins MIR1 and MIR2 and has similar activity. J. Biol. Chem.2003; 278:14657-68. ; Ohmura-Hoshino M, Goto E, Matsuki Y, et al. A novel family of membrane-bound E3 ubiquitin ligases. J. Biochem.2006; 140:147-54.; Bartee E, Mansouri M, Hovey Nerenberg BT, et al. Downregulation of major histocompatibility complex class I by human ubiquitin ligases related to viral immune evasion proteins. J. Virol.2004; 78:1109-20.
Shipping Conditions
Wet Ice
Applications Notes
MARCH8 antibody can be used for detection of MARCH8 by Western blot at 0.5 - 1 ug/ml. (Optimal dilution should be determined by user)
NCBI Gene Symbol
44993
NCBI GB Accession Number
44993
Host or Source
Rabbit
Protein Name
E3 ubiquitin-protein ligase MARCH8
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog