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Spred1 Antibody : FITC (OAPB00769-FITC)

Product Specifications

Gene Aliases

LGSS, NFLS, hSpred1, spred-1, PPP1R147

Gene ID

161742

Swiss Prot

Q7Z699

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

The immunogen for anti-Spred1 antibody: antibody was raised against a 14 amino acid peptide near the center of the human Spred1.

Target

(IN2) Sprouty-related EVH1 domain-containing protein 1

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

ELISA, WB, IHC

Purification

Affinity chromatography purified via peptide column

Concentration

1 mg/ml

Homology

Human; Mouse; Rat

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

References & Citations

Wakioka T, Sasaki A, Kato R, et al. Spred is a Sprouty-related suppressor of Ras signalling. Nature2001; 412:647-51.; Minowada G, Jarvis LA, Chi CL, et al. Vertebrate Sprouty genes are induced by FGF signaling and can cause chondrodysplasia when overexpressed. Development1999; 126:4465-75.; Lee SH, Schloss DJ, Jarvis L, et al. Inhibition of angiogenesis by a mouse sprouty protein. J. Biol. Chem.2001; 276:4128-33.; Yoshida T, Hisamoto T, Akiba J, et al. Spreds, inhibitors of the Ras/ERK signal transduction, are dysregulated in human hepatocellular carcinoma and linked to the malignant phenotype of tumors. Oncogene2006; 25:6056-66.

Shipping Conditions

Wet Ice

Applications Notes

Spred1 antibody can be used for detection of Spred1 by Western blot at 1 - 2 ug/ml. (Optimal dilution should be determined by user)

NCBI Gene Symbol

SPRED1

NCBI GB Accession Number

SPRED1

Host or Source

Rabbit

Protein Name

Sprouty-related, EVH1 domain-containing protein 1

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