ASAH2 Antibody : Biotin (OAPB00727-Biotin)
Product Specifications
Gene Aliases
HNAC1, BCDase, LCDase, NCDase, N-CDase
Gene ID
56624
Swiss Prot
Q9NR71
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
The immunogen for anti-ASAH2 antibody: antibody was raised against a 17 amino acid peptide near the carboxy terminus of the human ASAH2.
Target
Non-lysosomal ceramidase
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
ELISA, WB
Purification
Affinity chromatography purified via peptide column
Concentration
1 mg/ml
Homology
Human; Mouse; Rat
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
References & Citations
Nilsson A and Duan RD. Alkaline sphingomyelinases and ceramidases of the gastrointestinal tract. Chem. Phys. Lipids1999; 102:97-105.; Tani M, Okino N, Mitsutake S, et al. Molecular Cloning of the Full-length cDNA Encoding Mouse Neutral Ceramidase. J. Biol. Chem.2000; 275:11229-34.; Tani M, Iida H, and Ito M. O-Glycosylation of Mucin-like Domain Retains the Neutral Ceramidase on the Plasma Membranes as a Type II Integral Membrane Protein. J. Biol. Chem.2003; 278:10523-30.; Osawa Y, Uchinami H, Bielawski J, et al. Roles for C16-ceramide and sphingosine 1-phosphate in regulating hepatocyte apoptosis in response to tumor necrosis factor-alpha. J. Biol. Chem.2005; 280:27879-87.
Shipping Conditions
Wet Ice
Applications Notes
ASAH2 antibody can be used for detection of ASAH2 by Western blot at 1 ug/ml. (Optimal dilution should be determined by user)
NCBI Gene Symbol
ASAH2
NCBI GB Accession Number
ASAH2
Host or Source
Rabbit
Protein Name
Neutral ceramidase
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