ASAH1 Antibody : FITC (OAPB00726-FITC)
Product Specifications
Gene Aliases
AC, PHP, ASAH, PHP32, ACDase, SMAPME
Gene ID
427
Swiss Prot
Q13510
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
The immunogen for anti-ASAH1 antibody: antibody was raised against a 16 amino acid peptide near the carboxy terminus of the human ASAH1.
Target
An acid ceramidase
Clonality
Polyclonal
Conjugation
FITC: Fluorescein Isothiocyanate
Type
Polyclonal Antibody
Applications
ELISA, WB, IHC
Purification
Affinity chromatography purified via peptide column
Concentration
1 mg/ml
Homology
Multiple isoforms of ASAH1 are known to exist.
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
References & Citations
Nilsson A and Duan RD. Alkaline sphingomyelinases and ceramidases of the gastrointestinal tract. Chem. Phys. Lipids1999; 102:97-105.; Koch J, Gartner S, Li CM, et al. Molecular cloning and characterization of a full-length complementary DNA encoding human acid ceramidase. Identification of the first molecular lesion causing Farber’s disease. J. Biol. Chem.1996; 271:33110-5.; Li CM, Park JH, Simonaro CM, et al. Insertional mutagenesis of the mouse acid ceramidase gene leads to early embryonic lethality in homozygotes and progressive lipid storage disease in heterozygotes. Genomics2002; 79:218-24.; He X, Huang Y, Li B. Deregulation of sphingolipid metabolism in Alzheimer’s disease. Neurobiol. Aging2008; epub.
Shipping Conditions
Wet Ice
Applications Notes
ASAH1 antibody can be used for detection of ASAH1 by Western blot at 1 ug/ml. (Optimal dilution should be determined by user)
NCBI Gene Symbol
ASAH1
NCBI GB Accession Number
ASAH1
Host or Source
Rabbit
Protein Name
Acid ceramidase
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