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ASAH1 Antibody : FITC (OAPB00726-FITC)

Product Specifications

Gene Aliases

AC, PHP, ASAH, PHP32, ACDase, SMAPME

Gene ID

427

Swiss Prot

Q13510

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

The immunogen for anti-ASAH1 antibody: antibody was raised against a 16 amino acid peptide near the carboxy terminus of the human ASAH1.

Target

An acid ceramidase

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

ELISA, WB, IHC

Purification

Affinity chromatography purified via peptide column

Concentration

1 mg/ml

Homology

Multiple isoforms of ASAH1 are known to exist.

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

References & Citations

Nilsson A and Duan RD. Alkaline sphingomyelinases and ceramidases of the gastrointestinal tract. Chem. Phys. Lipids1999; 102:97-105.; Koch J, Gartner S, Li CM, et al. Molecular cloning and characterization of a full-length complementary DNA encoding human acid ceramidase. Identification of the first molecular lesion causing Farber’s disease. J. Biol. Chem.1996; 271:33110-5.; Li CM, Park JH, Simonaro CM, et al. Insertional mutagenesis of the mouse acid ceramidase gene leads to early embryonic lethality in homozygotes and progressive lipid storage disease in heterozygotes. Genomics2002; 79:218-24.; He X, Huang Y, Li B. Deregulation of sphingolipid metabolism in Alzheimer’s disease. Neurobiol. Aging2008; epub.

Shipping Conditions

Wet Ice

Applications Notes

ASAH1 antibody can be used for detection of ASAH1 by Western blot at 1 ug/ml. (Optimal dilution should be determined by user)

NCBI Gene Symbol

ASAH1

NCBI GB Accession Number

ASAH1

Host or Source

Rabbit

Protein Name

Acid ceramidase

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