Ambra1 Antibody : HRP (OAPB00663-HRP)
Product Specifications
Gene Aliases
DCAF3, WDR94
Gene ID
55626
Swiss Prot
Q9C0C7
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
The immunogen for anti-Ambra1 antibody: antibody was raised against a 18 amino acid peptide from near the amino terminus of human Ambra1.
Target
(NT) autophagy regulating protein
Clonality
Polyclonal
Conjugation
HRP: Horseradish Peroxidase
Type
Polyclonal Antibody
Applications
ELISA, WB, IHC
Purification
Affinity chromatography purified via peptide column
Concentration
0.6-0.7 mg/ml
Homology
Human; Mouse
Format
Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
References & Citations
Gozuacik D and Kimchi A. Autophagy as a cell death and tumor suppressor mechanism. Oncogene2004; 23:2891-906.; Kisen GO, Tessitore L, Costelli P, et al. Reduced autophagic activity in primary rat hepatocellular carcinoma and ascites hepatoma cells. Carcinogenesis1993; 14:2501-5.; Liang XH, Jackson S, Seaman M, et al. Induction of autophagy and inhibition of tumorigenesis by beclin 1. Nature1999; 402:672-6.; Fimia GM, Stoykova A, Romagnoli A, et al. Ambra1 regulates autophagy and development of the nervous system. Nature2007; 447:1121-5.
Shipping Conditions
Wet Ice
Applications Notes
Ambra1 antibody can be used for the detection of Ambra1 by Western blot at 2 - 4 ug/ml. (Optimal dilution should be determined by user)
NCBI Gene Symbol
AMBRA1
NCBI GB Accession Number
AMBRA1
Host or Source
Rabbit
Protein Name
Activating molecule in BECN1-regulated autophagy protein 1
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