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Ambra1 Antibody : HRP (OAPB00662-HRP)

Selected Variant

OAPB00662-100UG-HRP

Size: 0.1 mg

Product Specifications

Gene Aliases

DCAF3, WDR94

Gene ID

55626

Swiss Prot

Q9C0C7

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

The immunogen for anti-Ambra1 antibody: antibody was raised against a 15 amino acid peptide from near the carboxy terminus of human Ambra1.

Target

(CT) autophagy regulating protein

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

ELISA, WB, IHC

Purification

Affinity chromatography purified via peptide column

Concentration

0.6-0.7 mg/ml

Homology

Human; Mouse; Rat

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

References & Citations

Gozuacik D and Kimchi A. Autophagy as a cell death and tumor suppressor mechanism. Oncogene2004; 23:2891-906.; Kisen GO, Tessitore L, Costelli P, et al. Reduced autophagic activity in primary rat hepatocellular carcinoma and ascites hepatoma cells. Carcinogenesis1993; 14:2501-5.; Liang XH, Jackson S, Seaman M, et al. Induction of autophagy and inhibition of tumorigenesis by beclin 1. Nature1999; 402:672-6.; Fimia GM, Stoykova A, Romagnoli A, et al. Ambra1 regulates autophagy and development of the nervous system. Nature2007; 447:1121-5.

Shipping Conditions

Wet Ice

Applications Notes

Ambra1 antibody can be used for the detection of Ambra1 by Western blot at 1 - 2 ug/ml. (Optimal dilution should be determined by user)

NCBI Gene Symbol

AMBRA1

NCBI GB Accession Number

AMBRA1

Host or Source

Rabbit

Protein Name

Activating molecule in BECN1-regulated autophagy protein 1

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