IRGM Antibody : FITC (OAPB00657-FITC)
Product Specifications
Gene Aliases
IFI1, IRGM1, LRG47, LRG-47
Gene ID
345611
Swiss Prot
A1A4Y4
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
The immunogen for anti-IRGM antibody: antibody was raised against a 14 amino acid peptide near the center of the human IRGM.
Target
(IN) gamma-interferon-induced GTP-binding protein
Clonality
Polyclonal
Conjugation
FITC: Fluorescein Isothiocyanate
Type
Polyclonal Antibody
Applications
ELISA, WB, IHC
Purification
Affinity chromatography purified via peptide column
Concentration
1 mg/ml
Homology
Human; Mouse; Rat
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
References & Citations
Gozuacik D and Kimchi A. Autophagy as a cell death and tumor suppressor mechanism. Oncogene2004; 23:2891-906.; Massey DC and Parkes M. Genome-wide association scanning highlights two autophagy genes, ATG16L1 and IRGM, as being significantly associated with Crohn's disease. Autophagy2007; 3:649-51.; Fisher SA, Tremelling M, Anderson CA, et al. Genetic determinants of ulcerative colitis include the ECM1 locus and five loci implicated in Crohn's disease. Nat. Genet.2008; 40:710-2. ; Singh SB, Davis AS, Taylor GA, et al. Human IRGM induces autophagy to eliminate intracellular mycobacteria. Science2006; 313:1438-41.
Shipping Conditions
Wet Ice
Applications Notes
IRGM antibody can be used for detection of IRGM by Western blot at 1 - 2 ug/ml. (Optimal dilution should be determined by user)
NCBI Gene Symbol
IRGM
NCBI GB Accession Number
IRGM
Host or Source
Rabbit
Protein Name
Immunity-related GTPase family M protein
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