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SIRT2 Antibody : FITC (OAPB00636-FITC)

Product Specifications

Gene Aliases

SIR2, SIR2L, SIR2L2

Gene ID

22933

Swiss Prot

Q8IXJ6

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

The immunogen for anti-SIRT2 antibody: antibody was raised against a 19 amino acid peptide near the carboxy terminus of the human SIRT2.

Target

(CT) Sirtuin 2

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

ELISA, WB, IHC

Purification

Affinity chromatography purified via peptide column

Concentration

1 mg/ml

Homology

Human; Mouse; Rat

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

References & Citations

Yamamoto H, Schoonjans K, and Auwerx J. Sirtuin functions in health and disease. Mol. Endocrinol.2007; 21:1745-55.; Frye RA. Characterization of five human cDNAs with homology to the yeast SIR2 gene: SIR2-like proteins (sirtuins) metabolize NAD and may have protein ADP-ribosyltransferase activity. Biochem. Biophys. Res. Commun.1999; 260:273-279.; North BJ, Marshall BL, Borra MT, et. al. The human Sir2 ortholog, SIRT2, is an NAD+-dependent tubulin deacetylase. Mol. Cell2003; 11:437-44.; Inoue T, Hiratsuka M, Osaki M, et al. The molecular biology of mammalian SIRT proteins: SIRT2 in cell cycle regulation. Cell Cycle2007; 6:1011-8.

Shipping Conditions

Wet Ice

Applications Notes

SIRT2 antibody can be used for detection of SIRT2 by Western blot at 1 - 2 ug/ml. (Optimal dilution should be determined by user)

NCBI Gene Symbol

SIRT2

NCBI GB Accession Number

SIRT2

Host or Source

Rabbit

Protein Name

NAD-dependent protein deacetylase sirtuin-2

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