BRCC36 Antibody : HRP (OAPB00572-HRP)
Product Specifications
Gene Aliases
C6.1A, BRCC36, CXorf53
Gene ID
79184
Swiss Prot
P46736
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
The immunogen for anti-BRCC36 antibody: antibody was raised against a 18 amino acid peptide from near the amino terminus of human BRCC36.
Target
BRCA1/BRCA2-containing complex subunit 3
Clonality
Polyclonal
Conjugation
HRP: Horseradish Peroxidase
Type
Polyclonal Antibody
Applications
ELISA, WB, IHC
Purification
Affinity chromatography purified via peptide column
Concentration
0.6-0.7 mg/ml
Homology
Human; Mouse; Rat
Format
Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
References & Citations
Dong Y, Hakimi MA, Chen X, et al. Regulation of BRCC, a holoenzyme complex containing BRCA1 and BRCA2, by a signalsome-like subunit and its role in DNA repair. Mol. Cell2003; 12:1087-99.; Chen X, Arciero CA, Wang C, et al. BRCC36 is essential for ionizing radiation-induced BRCA1 phosphorylation and nuclear foci formation. Cancer Res.2006; 66:5039-46.
Shipping Conditions
Wet Ice
Applications Notes
BRCC36 antibody can be used for detection of BRCC36 by Western blot at 0.5 - 1 ug/ml. (Optimal dilution should be determined by user)
NCBI Gene Symbol
BRCC3
NCBI GB Accession Number
BRCC3
Host or Source
Rabbit
Protein Name
Lys-63-specific deubiquitinase BRCC36
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