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DISC1 Antibody : HRP (OAPB00558-HRP)

Product Specifications

Gene Aliases

C3PO, TRAX

Gene ID

7257

Swiss Prot

Q99598

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

The immunogen for anti-DISC1 antibody: antibody was raised against a 18 amino acid peptide from near the center of human DISC1.

Target

(IN) Disrupted in schizophrenia 1

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

ELISA, WB, ICC

Purification

Affinity chromatography purified via peptide column

Concentration

0.6-0.7 mg/ml

Homology

Human; Mouse

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

References & Citations

Millar JK, Wilson-Annan JC, Anderson S, et al. Disruption of two novel genes by a translocation co-segregating with schizophrenia. Hum. Mol. Genet.2000; 9:1415-23.; Morris JA, Kandpal G, Ma L, et al. DISC1 (Disrupted-in-schizophrenia 1) is a centrosome-associated protein that interacts with MAP1A, MIPT3, ATF4/5 and NUDEL: regulation and loss of interaction with mutation. Hum. Mol. Genet.2003; 12:1591-608.; Taya S, Shinoda T, Tsuboi D, et al. DISC1 regulates the transport of the NUDEL/LIS1/14-3-3e complex through kinesin-1. J. Neurosci.2007; 27:15-26.; Duan X, Chang JH, Ge S, et al. Disrupted-in-schizophrenia 1 regulates integration of newly generated neurons in the adult brain. Cell2007; 1146-58.

Shipping Conditions

Wet Ice

Applications Notes

DISC1 antibody can be used for detection of DISC1 by Western blot at 1 - 2 ug/ml. (Optimal dilution should be determined by user)

NCBI Gene Symbol

TSNAX

NCBI GB Accession Number

TSNAX

Host or Source

Rabbit

Protein Name

Translin-associated protein X

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