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MICA Antibody : FITC (OAPB00542-FITC)

Product Specifications

Gene Aliases

MIC-A, PERB11.1

Gene ID

100507436

Swiss Prot

Q29983

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

The immunogen for anti-MICA antibody: antibody was raised against a 16 amino acid peptide from near the carboxy terminus of human MICA.

Target

MHC class I chain-related protein A

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

ELISA, WB, IHC

Purification

Affinity chromatography purified via peptide column

Concentration

1 mg/ml

Homology

Human; Mouse

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

References & Citations

Rudolph MG, Stanfield RL and Wilson IA. How TCRs bind MHCs, peptides, and coreceptors. Annu. Rev. Immunol.2006; 24:419-66.; Bahram S, Bresnahan M, Geraghty DE, et al. A second lineage of mammalian major histocompatibility complex I genes. Proc. Natl. Acad. Sci. USA1994; 91:6259-63.; Bauer S, Groh V, Wu J, et al. Activation of NK cells and T cells by NKG2D, a receptor for stress-inducible MICA. Science1999; 285:727-9.; Maccalli C, Pende D, Castelli C, et al. NKG2D engagement of colorectal cancer-specific T cells strengthens TCR-mediated antigen stimulation and elicits TCR independent anti-tumor activity. Eur. J. Immunol.2003; 33:2033-43.

Shipping Conditions

Wet Ice

Applications Notes

MICA antibody can be used for detection of MICA by Western blot at 0.5 - 1 ug/ml. (Optimal dilution should be determined by user)

NCBI Gene Symbol

MICA

NCBI GB Accession Number

MICA

Host or Source

Rabbit

Protein Name

MHC class I polypeptide-related sequence A

Frequently Asked Questions

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