NK3R Antibody : HRP (OAPB00540-HRP)
Product Specifications
Gene Aliases
NK3, NKR, HH11, NK3R, NK-3R, TAC3R, TAC3RL
Gene ID
6870
Swiss Prot
P29371
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
The immunogen for anti-NK3R antibody: antibody was raised against a 18 amino acid peptide from near the center of human NK3R.
Target
(IN) Neurokinin B receptor
Clonality
Polyclonal
Conjugation
HRP: Horseradish Peroxidase
Type
Polyclonal Antibody
Applications
ELISA, WB, IHC
Purification
Affinity chromatography purified via peptide column
Concentration
0.6-0.7 mg/ml
Homology
Human; Mouse
Format
Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
References & Citations
Maggi CA. The mammalian tachykinin receptors. Gen. Pharmacol.1995; 26:911-44.; Ding Y-Q, Shi J, Su L-Y, et al. Receptor (NK3) -containing neurons in the paraventricular and supraoptic nuclei of the rat hypothalamus synthesize vasopressin and express fos following intravenous injection of hypotonic saline. Neurosci.1999; 91:1077-85.; Nakajima Y, Tsuchida K, Negishi M, et al. Direct linkage of three tachykinin receptors to stimulation of both phosphatidylinositol hydrolysis and cyclic AMP cascades in transfected Chinese hamster ovary cells. J. Biol. Chem.1992; 267:2437-42.; Haley GE and Flynn FW. Tachykinin NK3 receptor contribution to systemic release of vasopressin and oxytocin in response to osmotic and hypotensive challenge. Am. J. Regul. Integr. Comp. Physiol.2007; 293:R931-7.
Shipping Conditions
Wet Ice
Applications Notes
NK3R antibody can be used for detection of NK3R by Western blot at 0.5 - 1 ug/ml. (Optimal dilution should be determined by user)
NCBI Gene Symbol
TACR3
NCBI GB Accession Number
TACR3
Host or Source
Rabbit
Protein Name
Neuromedin-K receptor
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