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NK3R Antibody : HRP (OAPB00540-HRP)

Product Specifications

Gene Aliases

NK3, NKR, HH11, NK3R, NK-3R, TAC3R, TAC3RL

Gene ID

6870

Swiss Prot

P29371

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

The immunogen for anti-NK3R antibody: antibody was raised against a 18 amino acid peptide from near the center of human NK3R.

Target

(IN) Neurokinin B receptor

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

ELISA, WB, IHC

Purification

Affinity chromatography purified via peptide column

Concentration

0.6-0.7 mg/ml

Homology

Human; Mouse

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

References & Citations

Maggi CA. The mammalian tachykinin receptors. Gen. Pharmacol.1995; 26:911-44.; Ding Y-Q, Shi J, Su L-Y, et al. Receptor (NK3) -containing neurons in the paraventricular and supraoptic nuclei of the rat hypothalamus synthesize vasopressin and express fos following intravenous injection of hypotonic saline. Neurosci.1999; 91:1077-85.; Nakajima Y, Tsuchida K, Negishi M, et al. Direct linkage of three tachykinin receptors to stimulation of both phosphatidylinositol hydrolysis and cyclic AMP cascades in transfected Chinese hamster ovary cells. J. Biol. Chem.1992; 267:2437-42.; Haley GE and Flynn FW. Tachykinin NK3 receptor contribution to systemic release of vasopressin and oxytocin in response to osmotic and hypotensive challenge. Am. J. Regul. Integr. Comp. Physiol.2007; 293:R931-7.

Shipping Conditions

Wet Ice

Applications Notes

NK3R antibody can be used for detection of NK3R by Western blot at 0.5 - 1 ug/ml. (Optimal dilution should be determined by user)

NCBI Gene Symbol

TACR3

NCBI GB Accession Number

TACR3

Host or Source

Rabbit

Protein Name

Neuromedin-K receptor

Frequently Asked Questions

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