RTN4 Antibody : Biotin (OAPB00512-Biotin)

Product Specifications

Gene Name

Reticulon-4

Gene Aliases

ASY, NSP, NOGO, RTN-X, NSP-CL, RTN4-A, RTN4-C, RTN4-B1, RTN4-B2, NI220/250, Nbla00271, Nbla10545

Gene ID

57142

Swiss Prot

Q9NQC3

Accession Number

NP_008939.1NP_065393.1NP_722550.1NP_997403.1NP_997404.1XP_005264491.1

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

The immunogen for anti-NogoA antibody: antibody was raised against a 19 amino acid peptide from near the center of human NogoA.

Target

(IN) a myelin-associated neurite outgrowth inhibitor

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

ELISA, WB, IHC

Purification

Affinity chromatography purified via peptide column

Concentration

1 mg/ml

Homology

Human; Mouse; Rat

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

References & Citations

Yan R, ShiQ, Hu X, et al. Reticulon proteins: emerging players in neurodegenerative diseases. Cell. Mol. Life Sci.2006; 63:877-889.; Chen MS, Huber AB, van der Haar ME, et al. Nogo-A is a myelin-associated neurite outgrowth inhibitor and an antigen for monoclonal antibody IN-1. Nature2000; 403:434-9.; Schweigreiter R and Bandtlow CE. Nogo in the injured spinal cord. J. Neurotrauma2006; 3-4:384-96.; Dupuis L, Gonzalez de Aguilar JL, di Scala F, et al. Nogo provides a molecular marker for diagnosis of amyloid lateral sclerosis. Neurobiol. Dis.2002; 10:358-65.