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IFIH1 Antibody : Biotin (OAPB00490-Biotin)

Product Specifications

Gene Name

Interferon-induced helicase C domain-containing protein 1

Gene Aliases

AGS7, Hlcd, MDA5, MDA-5, RLR-2, IDDM19, SGMRT1

Gene ID

64135

Swiss Prot

Q9BYX4

Accession Number

NP_071451.2

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

The immunogen for anti-MDA5 antibody: antibody was raised against a 16 amino acid peptide from near the carboxy terminus of human MDA5.

Target

(CT) Melanoma differentiation-associated protein 5

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

ELISA, WB, IHC

Purification

Affinity chromatography purified via peptide column

Concentration

1 mg/ml

Homology

Human; Mouse

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

References & Citations

Akira S, Uematsu S, and Takeuchi O. Pathogen recognition and innate immunity. Cell 2006; 124:783-801.; Hiscott J, Nguyen T-LA, Arguello M, et al. Manipulation of the nuclear factor-B pathway and the innate immune response by viruses. Oncogene 2006; 25:6844-67.; Kang D, Gopalrishnan RV, Lin L, et al. Expression analysis and genomic characterization of human melanoma differentiation associated gene-5, mda-5: a novel type I interferon-responsive apoptosis-inducing gene. Oncogene 2004; 23:1789-800.; Andrejeva J, Childs KS, Young DF, et al. The V proteins of the paramyxoviruses bind the IFN-inducible RNA helicase, mda-5, and inhibit its activation of the IFN-beta promoter. Proc. Natl. Acad. Sci. USA 2004; 101:17264-9.

Shipping Conditions

Wet Ice

Applications Notes

MDA5 antibody can be used for detection of MDA5 by Western blot at 1 - 2 ug/ml. (Optimal dilution should be determined by user)

NCBI Gene Symbol

IFIH1

NCBI GB Accession Number

IFIH1

Host or Source

Rabbit

Protein Name

Interferon-induced helicase C domain-containing protein 1

Nucleotide Accession Number

NM_022168.3

Frequently Asked Questions

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