EMD Antibody : Biotin (OAPB00487-Biotin)
Product Specifications
Gene Name
Emerin
Gene Aliases
STA, EDMD, LEMD5
Gene ID
2010
Swiss Prot
P50402
Accession Number
NP_000108.1
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
The immunogen for anti-Emerin antibody: antibody was raised against a 19 amino acid peptide from near the amino terminus of human Emerin.
Target
A serine-rich nuclear membrane member of the nuclear lamina-associated protein family
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
ELISA, WB, IHC
Purification
Affinity chromatography purified via peptide column
Concentration
1 mg/ml
Homology
Human; Mouse; Rat
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
References & Citations
Schirmer EC, Florens L, Guan T, et al. Nuclear membrane proteins with potential disease links found by subtractive proteomics. Science 2003; 301:1380-2.; Cai M, Huang Y, Ghirlando R, et al. Solution structure of the constant region of nuclear envelope protein LAP2 reveals two LEM-domain structures: one binds BAF and the other binds DNA. EMBO J. 2001; 20:4399-407.; Chen H and Engelman A. The barrier-to-autointegration protein is a host factor for HIV type 1 integration. Proc. Natl. Acad. Sci. USA 1998; 95:15270-4.; Hutchison CJ. Lamins: building blocks or regulators of gene expression? Nat. Rev. Mol. Cell Biol. 2002; 3:848-58.
Shipping Conditions
Wet Ice
Applications Notes
Emerin antibody can be used for detection of Emerin by Western blot at 0.5 - 1 ug/ml. (Optimal dilution should be determined by user)
NCBI Gene Symbol
EMD
NCBI GB Accession Number
EMD
Host or Source
Rabbit
Protein Name
Emerin
Nucleotide Accession Number
NM_000117.2
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