Cbl Antibody : FITC (OAPB00462-FITC)
Product Specifications
Gene Aliases
CBL2, NSLL, C-CBL, RNF55, FRA11B
Gene ID
867
Swiss Prot
P22681
Accession Number
P22681
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
The immunogen for anti-Cbl antibody: antibody was raised against a 14 amino acid peptide from near the carboxy terminus of human cbl.
Target
A ubiquitin conjugating enzyme
Clonality
Polyclonal
Conjugation
FITC: Fluorescein Isothiocyanate
Type
Polyclonal Antibody
Applications
ELISA, WB, IF
Purification
Affinity chromatography purified via peptide column
Concentration
1 mg/ml
Homology
Human; Mouse; Rat
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
References & Citations
Thien CBF and Langdon WY. C-Cbl and Cbl-b ubiquitin ligases: substrate diversity and the negative regulation of signaling responses. Biochem. J. 2005; 391:153-66; Weissman AM. Themes and variations on ubiquitylation. Nat. Rev. Mol. Cell Biol. 2001; 2:169-78.; Swaminathan G and Tsygankov AY. The Cbl family of proteins: ring leaders in regulation of cell signaling. J. Cell. Physiol. 2006; 209:21-43.
Shipping Conditions
Wet Ice
Applications Notes
Cbl antibody can be used for detection of cbl by Western blot at 0.5 - 1 ug/ml. (Optimal dilution should be determined by user)
NCBI Gene Symbol
CBL
NCBI GB Accession Number
Cbl
Host or Source
Rabbit
Protein Name
E3 ubiquitin-protein ligase CBL
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