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TNFRSF11A Antibody : Biotin (OAPB00460-Biotin)

Product Specifications

Gene Name

Tumor necrosis factor receptor superfamily member 11A

Gene Aliases

FEO, OFE, ODFR, OSTS, PDB2, RANK, CD265, OPTB7, TRANCER, LOH18CR1, TRANCE-R

Gene ID

8792

Swiss Prot

Q9Y6Q6

Accession Number

NP_001257878.1NP_001257879.1NP_001257880.1NP_001265197.1NP_003830.1

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

The immunogen for anti-sRANK Ligand antibody: antibody was raised against a 14 amino acid peptide from near the center of human sRANK-L.

Target

A member of the TNF-ligand family

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

ELISA, WB, IHC

Purification

Affinity chromatography purified via peptide column

Concentration

1 mg/ml

Homology

Human; Mouse; Rat

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

References & Citations

Wong BR, Rho J, Arron J, et al. TRANCE is a novel ligand of the tumor necrosis factor receptor family that activates c-Jun N-terminal kinase in T cells. J. Biol. Chem.1997; 272:25190-4.; Kong YY, Yoshida H, Sarosi I, et al. OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymph-node organogenesis. Nature 1999; 397:315-23.; Weitzmann MN, Cenci S, Rifas L, et al. Interleukin-7 stimulates osteoclast formation by up-regulating the T-cell production of soluble osteoclastogenic cytokines. Blood 2000; 96:1873-8.; Bharti AC, Takada Y, Shishodia S, et al. Evidence that receptor activator of the nuclear factor (NF) -kappaB ligand can suppress cell proliferation and induce apoptosis through activation of a NF-kappaB-independent and TRAF6-dependent mechanism. J. Biol. Chem.2004; 279:6065-76.

Shipping Conditions

Wet Ice

Applications Notes

SRANK-L antibody can be used for detection of sRANK-L by Western blot at 0.25 - 0.5 ug/ml. (Optimal dilution should be determined by user)

NCBI Gene Symbol

TNFRSF11A

NCBI GB Accession Number

TNFRSF11A

Host or Source

Rabbit

Protein Name

Tumor necrosis factor receptor superfamily member 11A

Nucleotide Accession Number

NM_001270949.1NM_001270950.1NM_001270951.1NM_001278268.1NM_003839.3

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