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TANK Antibody : Biotin (OAPB00433-Biotin)

Product Specifications

Gene Name

TRAF family member-associated NF-kappa-B activator

Gene Aliases

ITRAF, TRAF2, I-TRAF

Gene ID

10010

Swiss Prot

Q92844

Accession Number

NP_001186064.1NP_004171.2NP_597841.1

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

The immunogen for anti-TANK antibody: antibody was raised against a 14 amino acid peptide from near the carboxy terminus of human TANK.

Target

(CT) TRAF, TBK1, innate immunity

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

ELISA, WB, IHC

Purification

Affinity chromatography purified via peptide column

Concentration

1 mg/ml

Homology

Human; Mouse; Rat

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

References & Citations

Cheng G and Baltimore D. TANK, a co-inducer with TRAF2 of TNF- and CD40L-mediated NF-kappaB activation. Genes Dev. 1996; 10:963-73.; Rothe M, Xiong J, Shu HB, et al. I-TRAF is a novel TRAF-interacting protein that regulates TRAF-mediated signal transduction. Proc. Natl. Acad. Sci. USA 1996; 93:8241-6.; Pomerantz JL and Baltimore D. NF-kappaB activation by a signaling complex containing TRAF2, TANK and TBK1, a novel IKK-related kinase. EMBO J. 1999; 18:6694-704.; Chariot A, Leonardi A, Muller J, et al. Association of the adaptor TANK with the IkappaB kinase (IKK) regulator NEMO connects IKK complexes with the IKKepsilon and TBK1 kinases. J. Biol. Chem.2002; 277:37029-36.

Shipping Conditions

Wet Ice

Applications Notes

TANK antibody can be used for the detection of TANK by Western blot at 1 - 2 ug/ml. (Optimal dilution should be determined by user)

NCBI Gene Symbol

TANK

NCBI GB Accession Number

TANK

Host or Source

Rabbit

Protein Name

TRAF family member-associated NF-kappa-B activator

Nucleotide Accession Number

NM_001199135.1NM_004180.2NM_133484.1

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