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LY86 Antibody : HRP (OAPB00421-HRP)

Selected Variant

OAPB00421-100UG-HRP

Size: 0.1 mg

Product Specifications

Gene Name

Lymphocyte antigen 86

Gene Aliases

MD1, MD-1, MMD-1, dJ80N2.1

Gene ID

9450

Swiss Prot

O95711

Accession Number

NP_004262.1

Host

Rabbit

Reactivity

Human

Immunogen

The immunogen for anti-MD-1 antibody: antibody was raised against a 14 amino acid peptide from near the carboxy terminus of human MD-1.

Target

(CT) Toll-like receptor, TLR2, TLR4, RP105, MD-2

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

ELISA, WB, IHC

Purification

Affinity chromatography purified via peptide column

Concentration

0.6-0.7 mg/ml

Homology

Human

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

References & Citations

Takeda K, Kaisho T, and Akira S. Toll-like receptors. Annu. Rev. Immunol. 2003; 21:335-76.; Divanovic S, Trompette A, Atabani SF, et al. Inhibition of TLR-4/MD-2 signaling by RP105/MD-1. J. Endotoxin Res. 2005; 11:363-8.; Tsuneyoshi N, Fukudome K, Kohara J, et al. The functional and structural properties of MD-2 required for liposaccharide binding are absent in MD-1. J. Immunol. 2005; 174:340-4.; Nagai Y, Kobayashi T, Motoi Y, et al. The radioprotective 105/MD-1 complex links TLR2 and TLR4/MD-2 in antibody response to microbial membranes. J. Immunol. 2005; 174:7043-9.

Shipping Conditions

Wet Ice

Applications Notes

MD-1 antibody can be used for the detection of MD-1 by Western blot at 0.5 - 1 ug/ml. (Optimal dilution should be determined by user)

NCBI Gene Symbol

LY86

NCBI GB Accession Number

LY86

Host or Source

Rabbit

Protein Name

Lymphocyte antigen 86

Nucleotide Accession Number

NM_004271.3

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