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TIMD4 Antibody : HRP (OAPB00414-HRP)

Product Specifications

Gene Name

T-cell immunoglobulin and mucin domain-containing protein 4

Gene Aliases

TIM4, SMUCKLER

Gene ID

91937

Swiss Prot

Q96H15

Accession Number

NP_001140198.1NP_612388.2

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

The immunogen for anti-TIM-4 antibody: antibody was raised against a 15 amino acid peptide from near the carboxy terminus of human TIM-4.

Target

(CT) T cell immunoglobulin and mucin domain containing protein 4

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

ELISA, WB

Purification

Affinity chromatography purified via peptide column

Concentration

0.6-0.7 mg/ml

Homology

Human; Mouse; Rat

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

References & Citations

Meyers JH, Sabatos CA, Chakravarti S, et al. The TIM family regulates autoimmune and allergic diseases. Trends Mol. Med. 2005; 11:362-9.; Meyers JH, Chakravarti S, Schlesinger D, et al. TIM-4 is the ligand for TIM-1, and the TIM-1-TIM4 interaction regulates T cell proliferation. Nat. Immunol. 2005; 6:455-64.; Kuchroo VK, Umetsu DT, DeKruyff RH, et al. The TIM gene family: emerging roles in immunity and disease. Nat. Rev. Immunol. 2003; 3:454-62.; Shakhov AN, Rybtsov S, Tumanov AV, et al. SMUCKLER/TIM4 is a distinct member of TIM family expressed by stromal cells of secondary lymphoid tissues and associated with lymphotoxin signaling.

Shipping Conditions

Wet Ice

Applications Notes

TIM-4 antibody can be used for the detection of TIM-4 by Western blot at 1 - 2 ug/ml. (Optimal dilution should be determined by user)

NCBI Gene Symbol

TIMD4

NCBI GB Accession Number

TIMD4

Host or Source

Rabbit

Protein Name

T-cell immunoglobulin and mucin domain-containing protein 4

Nucleotide Accession Number

NM_001146726.1NM_138379.2

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