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CD5L Antibody : HRP (OAPB00411-HRP)

Product Specifications

Gene Name

CD5 antigen-like

Gene Aliases

AIM, API6, CT-2, hAIM, PRO229, Spalpha, SP-ALPHA

Gene ID

922

Swiss Prot

O43866

Accession Number

NP_005885.1XP_005245659.1

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

The immunogen for anti-AIM antibody: antibody was raised against a 16 amino acid peptide near the amino terminus of human AIM.

Target

(NT) apoptosis inhibitor of macrophages

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

ELISA, WB, IHC

Purification

Affinity chromatography purified via peptide column

Concentration

0.6-0.7 mg/ml

Homology

Human; Mouse

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

References & Citations

Miyazaki T, Hirokami Y, Matsuhashi N, et al. Increased susceptibility of thymocytes to apoptosis in mice lacking AIM, a novel murine macrophage-derived soluble factor belonging to the scavenger receptor cysteine-rich domain superfamily. J. Exp. Med. 1999; 189:413-22.; Biancone L, Bowen MA, Lim A, et al. Identification of a novel inducible cell-surface ligand of CD5 on activated lymphocytes. J. Exp. Med. 1996; 184:811-9.; Haruta I, Kato Y, Hashimoto E, et al. Association of AIM, a novel apoptosis inhibitory factor, with hepatitis via supporting macrophage survival and enhancing phagocytic function of macrophages. J. Biol. Chem.2001; 276:22910-4; Kuwata K, Watanabe H, Jiang S-Y, et al. AIM inhibits apoptosis of T cells and NKT cells in Corynebacterium-induced granuloma formation in mice. Am. J. Path. 2003; 162:837-47.

Shipping Conditions

Wet Ice

Applications Notes

AIM antibody can be used for the detection of AIM by Western blot at 1 - 2 ug/ml. (Optimal dilution should be determined by user)

NCBI Gene Symbol

CD5L

NCBI GB Accession Number

CD5L

Host or Source

Rabbit

Protein Name

CD5 antigen-like

Nucleotide Accession Number

NM_005894.2XM_005245602.1

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