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ECSIT Antibody : HRP (OAPB00256-HRP)

Product Specifications

Gene Name

Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial

Gene Aliases

SITPEC

Gene ID

51295

Swiss Prot

Q9BQ95

Accession Number

NP_001135936.1NP_001135937.1NP_001230133.1NP_057665.2

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

The immunogen for anti-ECSIT antibody: antibody was raised against a peptide corresponding to 14 amino acids near the C-terminus of human ECSIT.

Target

(CT) An intermediate in the TLR and Bmp signaling pathways

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

ELISA, WB, IHC

Purification

Ion exchange chromatography purified

Concentration

0.6-0.7 mg/ml

Homology

Human; Mouse

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

References & Citations

Takeda K, Kaisho T, and Akira S. Toll-like receptors. Annu. Rev. Immunol. 2003; 21:335-76.; Vogel SN, Fitzgerald KA, and Fenton MJ. TLRs: differential adapter utilization by toll-like receptors mediates TLR-specific patterns of gene expression. Mol. Interv. 2003; 3:466-77.; Janssens S and Beyaert R. Functional diversity and regulation of different interleukin-1 receptor-associated kinase (IRAK) family members. Mol. Cell. 2003; 11:293-302.; Sato S, Sugiyama M, Yamamoto M, et al. Toll/IL-1 receptor domain-containing adaptor inducing IFN-beta (TRIF) associates with TNF receptor-associated factor 6 and TANK-binding kinase 1, and activates two distinct transcription factors, NF-kappa B and IFN-regulatory factor-3, in the Toll-like receptor signaling. J. Immunol. 2003; 171 (8) :4304-10.

Shipping Conditions

Wet Ice

Applications Notes

ECSIT antibody can be used for detection of ECSIT by Western blot at 0.5 to 1 ug/ml. (Optimal dilution should be determined by user)

NCBI Gene Symbol

ECSIT

NCBI GB Accession Number

ECSIT

Host or Source

Rabbit

Protein Name

Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial

Nucleotide Accession Number

NM_001142464.2NM_001142465.2NM_001243204.1NM_016581.4

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