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APOBEC3G Antibody : Biotin (OAPB00226-Biotin)

Product Specifications

Gene Name

DNA dC->dU-editing enzyme APOBEC-3G

Gene Aliases

A3G, ARCD, ARP9, ARP-9, CEM15, CEM-15, MDS019, bK150C2.7, dJ494G10.1

Gene ID

60489

Swiss Prot

Q9HC16

Accession Number

NP_068594.1

Host

Rabbit

Reactivity

Human

Immunogen

The immunogen for anti-APOBEC3G antibody: antibody was raised against a synthetic peptide corresponding to 15 amino acids near the amino-terminus of human APOBEC3G.

Target

(NT) an HIV restriction factor

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

ELISA, WB, IHC

Purification

Affinity chromatography purified via peptide column

Concentration

1 mg/ml

Homology

Human

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

References & Citations

Jarmuz A, Chester A, Bayliss J, et al. An anthropoid-specific locus of Orphan C to U RNA-editing enzymes on chromosome 22. Genomics 2002; 79:285-96.; Stremlau M, Owens CM, Perron MJ, et al. The cytoplasmic body component TRIM5alpha restricts HIV-1 infection in Old World monkeys. Nature 2004; 427:848-53.; Bieniasz PD. Intrinsic immunity: a front-line defense against viral attack. Nat Immunol. 2004; 5:1109-15.; Sheehy AM, Gaddis NC, Choi JD, et al. Isolation of a human gene that inhibits HIV-1 infection and is suppressed by the viral Vif protein. Nature 2002; 418:646-50.

Shipping Conditions

Wet Ice

Specificity

APOBEC3G antibody will also detect the APOBEC3F isoform.

Applications Notes

APOBEC3G antibody can be used for detection of APOBEC3G by Western blot at 5 ug/ml. (Optimal dilution should be determined by user)

NCBI Gene Symbol

APOBEC3G

NCBI GB Accession Number

APOBEC3G

Host or Source

Rabbit

Protein Name

DNA dC->dU-editing enzyme APOBEC-3G

Nucleotide Accession Number

NM_021822.3

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