ARTS Antibody : HRP (OAPB00168-HRP)

The immunogen for anti-ARTS antibody: antibody was raised against a synthetic peptide corresponding to amino acids near the amino terminus of human ARTS.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Larisch S, Yi Y, Lotan R, Kerner H, et al. A novel mitochondrial septin-like protein, ARTS, mediates apoptosis dependent on its P-loop motif. Nat Cell Biol 2000;2 (12) :915-21 ; Depraetere V. The ARTS of apoptosis. Nat Cell Biol. 2000;2 (12) :E219.; Paavola, P., Horelli-Kuitunen, N., Palotie, A. and Peltonen, L. Characterization of a novel gene, PNUTL2, on human chromosome 17q22-q23 and its exclusion as the Meckel syndrome gene. Genomics 1999;55 (1) :122-125 ; Zieger, B., Tran, H., Hainmann, I. , Wunderle, D., Zgaga-Griesz, A., Blaser, S. and Ware, J. Characterization and expression analysis of two human septin genes, PNUTL1 and PNUTL2. Gene 2000;261 (2) :197-203

ARTS antibody can be used for detection of ARTS by Western blot at 0.5 to 2 ug/ml. Human lung, kidney and spleen tissue lysates can be used as a positive control and a band at 32 kDa can be detected. (Optimal dilution should be determined by user)