NOD2 Antibody : HRP (OAPB00158-HRP)
Product Specifications
Gene Name
Nucleotide-binding oligomerization domain-containing protein 2
Gene Aliases
CD, ACUG, BLAU, IBD1, YAOS, BLAUS, NLRC2, NOD2B, CARD15, CLR16.3, PSORAS1
Gene ID
64127
Swiss Prot
Q9HC29
Accession Number
NP_001280486.1NP_071445.1XP_005256141.1
Host
Rabbit
Reactivity
Human
Immunogen
The immunogen for anti-NOD2 antibody: antibody was raised against a synthetic peptide corresponding to 16 amino acids at the amino terminus of human NOD2.
Target
(NT) A new CARD-containing protein
Clonality
Polyclonal
Conjugation
HRP: Horseradish Peroxidase
Type
Polyclonal Antibody
Applications
ICC, ELISA, WB, IHC
Purification
Immunoaffinity chromatography purified IgG
Concentration
0.6-0.7 mg/ml
Homology
Human
Format
Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
References & Citations
Inohara N, Koseki T, del Peso L, et al. Nod1, an Apaf-1-like activator of caspase-9 and nuclear factor-kappaB. J. Biol. Chem. 1999; 274:14560-7.; Ogura Y, Inohara N, Benito A, et al. Nod2, a Nod1/Apaf-1 family member that is restricted to monocytes and activates NF-kappaB. J. Biol. Chem. 2001; 276:4812-8.; Hugot JP, Chamaillard M, et al. Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease. Nature 2001; 411:599-603.; Ogura Y, Bonen DK, Inohara N, et al. A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease. Nature 2001; 411:603-6.
Shipping Conditions
Wet Ice
Specificity
NOD2 has no cross-reaction with NOD1.
NCBI Gene Symbol
NOD2
NCBI GB Accession Number
NOD2
Host or Source
Rabbit
Protein Name
Nucleotide-binding oligomerization domain-containing protein 2
Nucleotide Accession Number
NM_001293557.1NM_022162.2XM_005256084.2
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