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NOD2 Antibody : FITC (OAPB00158-FITC)

Product Specifications

Gene Name

Nucleotide-binding oligomerization domain-containing protein 2

Gene Aliases

CD, ACUG, BLAU, IBD1, YAOS, BLAUS, NLRC2, NOD2B, CARD15, CLR16.3, PSORAS1

Gene ID

64127

Swiss Prot

Q9HC29

Accession Number

NP_001280486.1NP_071445.1XP_005256141.1

Host

Rabbit

Reactivity

Human

Immunogen

The immunogen for anti-NOD2 antibody: antibody was raised against a synthetic peptide corresponding to 16 amino acids at the amino terminus of human NOD2.

Target

(NT) A new CARD-containing protein

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

ICC, ELISA, WB, IHC

Purification

Immunoaffinity chromatography purified IgG

Concentration

1 mg/ml

Homology

Human

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

References & Citations

Inohara N, Koseki T, del Peso L, et al. Nod1, an Apaf-1-like activator of caspase-9 and nuclear factor-kappaB. J. Biol. Chem. 1999; 274:14560-7.; Ogura Y, Inohara N, Benito A, et al. Nod2, a Nod1/Apaf-1 family member that is restricted to monocytes and activates NF-kappaB. J. Biol. Chem. 2001; 276:4812-8.; Hugot JP, Chamaillard M, et al. Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease. Nature 2001; 411:599-603.; Ogura Y, Bonen DK, Inohara N, et al. A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease. Nature 2001; 411:603-6.

Shipping Conditions

Wet Ice

Specificity

NOD2 has no cross-reaction with NOD1.

NCBI Gene Symbol

NOD2

NCBI GB Accession Number

NOD2

Host or Source

Rabbit

Protein Name

Nucleotide-binding oligomerization domain-containing protein 2

Nucleotide Accession Number

NM_001293557.1NM_022162.2XM_005256084.2

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