IL21R Antibody : Biotin (OAPB00149-Biotin)

The immunogen for anti-IL-22 Receptor antibody: antibody was raised against a synthetic peptide corresponding to amino acids 560 to 574 of human IL-22 receptor precursor.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Dumoutier L, Louahed J, Renauld JC. Cloning and characterization of IL-10-related T cell-derived inducible factor (IL-TIF), a novel cytokine structurally related to IL-10 and inducible by IL-9. J Immunol. 2000;164 (4) :1814-9. ; Dumoutier L, Van Roost E, Colau D, Renauld JC.  Human interleukin-10-related T cell-derived inducible factor: molecular cloning and functional characterization as an hepatocyte-stimulating factor. Proc Natl Acad Sci USA . 2000 ;97 (18) :10144-9. ; Xie MH, Aggarwal S, Ho WH, et al. Interleukin (IL) -22, a novel human cytokine that signals through the interferon receptor-related proteins CRF2-4 and IL-22R. J Biol Chem. 2000;275 (40) :31335-9.; Kotenko SV, Izotova LS, Mirochnitchenko OV, et al. Identification of the functional interleukin-22 (IL-22) receptor complex: J Biol Chem. 2001;276 (4) :2725-32.

IL-22 receptor antibody can be used for detection of IL-22 receptor by Western blot at 0.5 to 1 ug/ml. An approximately 62 kDa band can be detected. (Optimal dilution should be determined by user)