IL21R Antibody : Biotin (OAPB00145-Biotin)

The immunogen for anti-IL-21 Receptor antibody: antibody was raised against a synthetic peptide corresponding to amino acids 20 to 32 of human IL-21 receptor precursor.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Parrish-Novak J, Dillon SR, Nelson A, et al. Interleukin 21 and its receptor are involved in NK cell expansion and regulation of lymphocyte function. Nature. 2000;408 (6808) :57-63. ; Ozaki K, Kikly K, Michalovich D, et al. Cloning of a type I cytokine receptor most related to the IL-2 receptor beta chain. Proc Natl Acad Sci USA . 2000;97 (21) :11439-44.; Asao H, Okuyama C, Kumaki S, et al. the common gamma-chain is an indispensable subunit of the IL-21 receptor complex. J Immunol. 2001;167 (1) :1-5. ; Vosshenrich CA, Di Santo JP. Cytokines: IL-21 joins the gamma (c) -dependent network Curr Biol. 2001;11 (5) :R175-7.

IL-21 receptor antibody can be used for detection of IL-21 receptor by Western blot at 0.5 to 1 ug/ml. An approximately 60 kDa band can be detected. (Optimal dilution should be determined by user)