IKBKAP Antibody : FITC (OAPB00123-FITC)

Product Specifications

Gene Name

Elongator complex protein 1

Gene Aliases

FD, DYS, IKAP, IKI3, TOT1, IKBKAP

Gene ID

8518

Swiss Prot

O95163

Accession Number

NP_003631.2

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

The immunogen for anti-IKAP antibody: antibody was raised against a 16 amino acid peptide from near the carboxy terminus of human IKAP.

Target

Part of the RNA polymerase II transcription elongation complex

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

ELISA, WB, ICC

Purification

Affinity chromatography purified via peptide column

Concentration

1 mg/ml

Homology

Human; Mouse

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

References & Citations

Cohen L, Henzel WJ, and Baeuerle PA. IKAP is a scaffold protein of the IkB kinase complex. Nature 1998; 395:292-6.; Krappmann D, Hatada EN, Tegethoff S, et al. The I kappa B kinase (IKK) complex is tripartite and contains IKK gamma but not IKAP as a regular component. J. Biol. Chem.2000; 275:29779-87.; Anderson SL, Coli R, Daly IW, et al. Familial dysautonomia is caused by mutations of the IKAP gene. Am. J. Hum. Genet. 2001; 68:753-8.; Hawkes NA, Otero G, Winkler GS, et al. Purification and characterization of the human elongator complex. J. Biol. Chem.2002; 277:3047-52.