IKBKAP Antibody : Biotin (OAPB00123-Biotin)
Product Specifications
Gene Name
Elongator complex protein 1
Gene Aliases
FD, DYS, IKAP, IKI3, TOT1, IKBKAP
Gene ID
8518
Swiss Prot
O95163
Accession Number
NP_003631.2
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
The immunogen for anti-IKAP antibody: antibody was raised against a 16 amino acid peptide from near the carboxy terminus of human IKAP.
Target
Part of the RNA polymerase II transcription elongation complex
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
ELISA, WB, ICC
Purification
Affinity chromatography purified via peptide column
Concentration
1 mg/ml
Homology
Human; Mouse
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
References & Citations
Cohen L, Henzel WJ, and Baeuerle PA. IKAP is a scaffold protein of the IkB kinase complex. Nature 1998; 395:292-6.; Krappmann D, Hatada EN, Tegethoff S, et al. The I kappa B kinase (IKK) complex is tripartite and contains IKK gamma but not IKAP as a regular component. J. Biol. Chem.2000; 275:29779-87.; Anderson SL, Coli R, Daly IW, et al. Familial dysautonomia is caused by mutations of the IKAP gene. Am. J. Hum. Genet. 2001; 68:753-8.; Hawkes NA, Otero G, Winkler GS, et al. Purification and characterization of the human elongator complex. J. Biol. Chem.2002; 277:3047-52.
Shipping Conditions
Wet Ice
Applications Notes
IKAP antibody can be used for detection of IKAP by Western blot at 0.5 to 1 ug/ml. (Optimal dilution should be determined by user)
NCBI Gene Symbol
IKBKAP
NCBI GB Accession Number
IKBKAP
Host or Source
Rabbit
Protein Name
Elongator complex protein 1
Nucleotide Accession Number
NM_003640.3
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