BIRC5 Antibody : HRP (OAPB00093-HRP)

The immunogen for anti-Survivin antibody: antibody was raised against a peptide corresponding to amino acids near the carboxy-terminus of human survivin.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Ambrosini G, Adida C, Altieri DC. A novel anti-apoptosis gene, survivin, expressed in cancer and lymphoma. Nat Med 1997;3:917-21 ; Li F, Ambrosini G, Chu EY, Plescia J, Tognin S, Marchisio PC, Altieri DC . Control of apoptosis and mitotic spindle checkpoint by survivin. Nature 1998;396:580-4; Kobayashi K, Hatano M, Otaki M, Ogasawara T, Tokuhisa T. Expression of a murine homologue of the inhibitor of apoptosis protein is related to cell proliferation. Proc Natl Acad Sci USA 1999;96:1457-62 (WD0600)

Survivin antibody can be used for detection of survivin by Western blot at 0.5 to 1 ug/ml. An approximate 17 kDa band should be detected. (Optimal dilution should be determined by user)