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DFFB Antibody : FITC (OAPB00076-FITC)

Product Specifications

Gene Name

DNA fragmentation factor subunit beta

Gene Aliases

CAD, CPAN, DFF2, DFF40, DFF-40

Gene ID

1677

Swiss Prot

O76075

Accession Number

NP_004393.1

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

The immunogen for anti-DFF40 antibody: antibody was raised against a peptide corresponding to amino acids 203 to 218 of human DFF40.

Target

(IN) Caspase Activated DNase

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

ICC, WB

Purification

Affinity chromatography purified via peptide column

Concentration

1 mg/ml

Homology

Human; Mouse; Rat

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

References & Citations

Enari M, Sakahira H, Yokoyama H, Okawa K, Iwamatsu A, Nagata S. A caspase-activated DNase that degrades DNA during apoptosis, and its inhibitor ICAD. Nature 1998;391:43-50 ; Sakahira H, Enari M, Nagata S. Cleavage of CAD inhibitor in CAD activation and DNA degradation during apoptosis. Nature 1998;391:96-99 ; Halenbeck R, MacDonald H, Roulston A, Chen TT, Conroy L, Williams LT. CPAN, a human nuclease regulated by the caspase-sensitive inhibitor DFF45. Curr Biol 1998;8:537-40 ; Liu X, Li P, Widlak P, Zou H, Luo X, Garrard WT, Wang X The 40-kDa subunit of DNA fragmentation factor induces DNA fragmentation and chromatin condensation during apoptosis. Proc Natl Acad Sci USA 1998;95:8461-6

Shipping Conditions

Wet Ice

NCBI Gene Symbol

DFFB

NCBI GB Accession Number

DFFB

Host or Source

Rabbit

Protein Name

DNA fragmentation factor subunit beta

Nucleotide Accession Number

NM_004402.3

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