FLIP Antibody : FITC (OAPB00045-FITC)
Product Specifications
Gene Aliases
EWSR2, SIC-1, BDPLT21
Gene ID
2313
Swiss Prot
Q01543
Accession Number
AAC51623
Host
Rabbit
Reactivity
Human
Immunogen
The immunogen for anti-FLIP antibody: antibody was raised against a peptide corresponding to amino acids 191 to 209 at C-terminus of human FLIP form2.
Target
(CT) FLICE inhibitory protein
Clonality
Polyclonal
Conjugation
FITC: Fluorescein Isothiocyanate
Type
Polyclonal Antibody
Applications
ELISA, WB, ICC, IHC-P, IF
Purification
Affinity chromatography purified via peptide column
Concentration
1 mg/ml
Homology
Human
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
References & Citations
Thome M, Schneider P, Hofmann K, Fickenscher H, Meinl E, Neipel F, Mattmann C, Burns K, Bodmer JL, Schroter M, Scaffidi C, Krammer PH, Peter ME, Tschopp J. Viral FLICE-inhibitory proteins (FLIPs) prevent apoptosis induced by death receptors. Nature 1997;386:517-521 ; Irmler M, Thome M, Hahne M, Schneider P, Hofmann K, Steiner V, Bodmer JL, Schroter M, Burns K, Mattmann C, Rimoldi D, French LE, Tschopp J. Inhibition of death receptor signals by cellular FLIP. Nature 1997;388:190-195 ; Shu HB, Halpin DR , Goeddel DV. Casper is a FADD- and caspase-related inducer of apoptosis. Immunity 1997;6:751-763 ; Hu S, Vincenz C, Ni J, Gentz R, Dixit VM. I-FLICE, a novel inhibitor of tumor necrosis factor receptor-1- and CD-95-induced apoptosis. J Biol Chem 1997;272:17255-17257
Shipping Conditions
Wet Ice
Specificity
Antibody recognizes human and murine FLIPgamma and FLIPdelta but not FLIPalpha and FLIPbeta.
Applications Notes
DcR2 antibody can be used for detection of DcR2 expression by Western blot at 1 ug/mL. Antibody can also be used for immunocytochemistry starting at 10 ug/mL and Immunohistochemistry starting at 2.5 ug/mL. For immunofluorescence start at 20 ug/mL.
NCBI Gene Symbol
FLIP
NCBI GB Accession Number
FLIP
Host or Source
Rabbit
Protein Name
Friend leukemia integration 1 transcription factor
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