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DVL2 Antibody (Phospho-Thr224) : Biotin (OABF01887-Biotin)

Product Specifications

Gene Name

Dishevelled segment polarity protein 2

Gene Aliases

Segment polarity protein dishevelled homolog DVL-2, Dishevelled-2, DSH homolog 2, DVL2

Gene ID

1856

Swiss Prot

O14641

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

KLH conjugated synthetic phosphopeptide derived from human DVL2 around the phosphorylation site of Thr224

Target

Participates in Wnt signaling by binding to the cytoplasmic C-terminus of frizzled family members and transducing the Wnt signal to down-stream effectors. Promotes internalization and degradation of frizzled proteins upon Wnt signaling. Plays a role both in canonical and non-canonical Wnt signaling. Plays a role in the signal transduction pathways mediated by multiple Wnt genes (By similarity) .

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB, IHC-P, IF

Purification

Purified by Protein A.

Concentration

1 mg/mL

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Shipping Conditions

Wet Ice

Fragment

IgG

NCBI Gene Symbol

DVL2

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